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Artificially reprogrammed macrophages as Tumor-Tropic Immunosuppression-Resistant biologics to realize therapeutics production and immune activation

Compounding this issue, certain mycotoxins have been shown in animal models to suppress the production of Diamine Oxidase (DAO), the primary enzyme responsible for breaking down dietary histamine in the gut

Pflugers Arch

PMID: 19289567 | doi:10.1124/jpet.108.149211 Greenwood-Van Meerveld B et al

Abstract Tumors exhibit metabolic fuel requirements resembling those of embryonic and other highly proliferative tissues, a similarity that can be exploited to combat neoplasia